Advanced Workshop | Basel
2023

Oct
5th—6th
2023

DRUG RESEARCH & DEVELOPMENT: CONTEMPORARY CHALLENGES AND SOLUTIONS

The workshop addresses experts working in preclinical and clinical development who would like to share perspectives in deciding the best clinical development strategy using adaptive & innovative designs and implementing new technologies. Based on the suggestions of the participants a selection of presentations will be made. To support networking, the number of participants is limited to 60 persons.

BRIDGING THE GAP BETWEEN OFFLINE AND ONLINE NETWORKING:

group exclusively for former and prospective participants in the event series

Image: Courtesy BaselArea.swiss

Details

Program

REGISTRATION

Free of charge (on invitation only – please contact organizers for further details)

LOCATIONS

Novartis Pavillon | St. Johanns-Hafen-Weg 5, 4056 Basel

Volta-Bräu | Voltastrasse 30, 4056 Basel

Switzerland Innovation Park Basel Area | Hegenheimermattweg 167A, 4123 Allschwil

ORGANIZERS

Dr. Klaus Francke
Bayer AG

Dr. Frank Otto Gombert
GPRS – Gombert Pharma Research Solutions

Dr. Ekkehard May
Nuvisan – Innovation
Campus Berlin (ICB)

Dr. Frank Richard
SOTIO Biotech AG

Dr. Grit Zahn
Eternygen GmbH

Dr. Frank S. Zollmann
Pharma Consult, CONELIS e.V.

Thursday, Oct 5th 2023
15:30 – 17:30	Visit of Novartis Pavillon and Campus Optional B2B meetings with companies located at Novartis Campus
18:00 – open end	Come-together @ Volta Bräu Interact with former, current and future colleagues

Friday, Oct 6th 2023
08:00	Registration
08:30	Welcome Address and Introduction into the Workshop
08:45	Individual Introduction of the Participants
09:15	Bridging the Gap: Translation from Animals to Humans in Biomedical Research Irena Adkins: Selection of in vivo models for drug development and translational challenges Lenka Palova: Current challenges in biomarker assessment Norman Liaw: Human cardiac stem cell models for complex disease modelling Wolfgang Moritz: Spheroids in Drug Development- An Emerging Technology Arrived in Routine
Coffee Break (10:35-11:00)
11:00	Fast-Tracking to Patients: Exploring New Clinical Approaches for Accelerated Access to Healthcare Innovations Peter McLennan: Application of AI to patient selection in clinical trials Jordi Guitart: Real-time patient selection for CTs using generative AI Isabelle Serve/Frank Richard: Paradigm shift in dose selection in oncology – clinical and regulatory aspects Natalia Muhlemann: Machine learning-based population selection and enrichment in late phases of drug development
12:00	Keynote lecture Nuria Kotecki: Future trends and new approaches in drug development
Lunch Break (12:30-13:30)
13:30	Revolutionizing Drug Development: Exploring New AI Tools and related Technologies Gillian Hertlein: AI enabled pharma R&D – Megatrends and Case Report (Toxicology) – Out of the Black Box: Explainable AI Tim Heinemann: Special cancer topic – „Enhancing precision medicine through in silico drug response predictions“ Corinne Sollier/ Diana Stoycheva: Biomarker discovery with single-cell and multi-omics data Jingwen Shi: AI-powered drug molecule prediction in chemical space Bridging the Gap: Translation from Animals to Humans in Biomedical Research (cont.) Mike Fossler: Innovative PKPD Modelling Approaches in preclinics and clinics
15:15	Workshop 2024 Brainstorming
Coffee Break
15:30	Closing